In its most up-to-date pointers on the usage of over-the-counter (OTC) medicine for COVID-19, the US Facilities for Illness Management and Prevention (CDC) says that mildly in poor health sufferers can relieve signs akin to fever and sore throat with acetaminophen or ibuprofen, however a staff led by Florida Atlantic College (FAU) researchers says it is not that straightforward..
In a evaluate within the American Journal of Medication, the investigators conclude that the choice to take acetaminophen (eg, Tylenol), aspirin, or ibuprofen (eg, Motrin, Advil) ought to be finished on a person foundation underneath the steerage of a clinician.
It is because the medicine aren’t risk-free, with overuse of acetaminophen tied to irreversible liver injury, liver failure, the necessity for liver transplant, and kidney injury, the authors famous.
Whereas aspirin’s anti-inflammatory properties could also be helpful in treating reasonable to extreme COVID-19, it carries the chance of bleeding, particularly within the gastrointestinal (GI) tract. That is of explicit concern in COVID-19, which can itself result in bleeding and clotting abnormalities.
Affected person profile ought to information resolution, authors say
In contrast with aspirin, ibuprofen, naproxen (eg, Aleve), and different non-steroidal anti-inflammatory medicine (NSAIDs) have higher adverse-event profiles, specifically for gastroenteritis (irritation of the GI tract) and peptic ulcers. As with acetaminophen, long-term use of those medicine can result in liver and kidney toxicity.
