Research says pomegranates could offer a solution to fatty liver disease

Researchers at Edith Cowan College (ECU) are investigating the consequences ellagic acid, an antioxidant present in some fruit and veggies, might have on halting and probably reversing the harm attributable to fatty liver illness.

Non-alcoholic fatty liver illness (NAFLD) is the physiological manifestation of weight problems within the liver. The prevalence of NAFLD has elevated from 25.24% in 2015 to 29.38% in 2021, and this situation now accounts for 45.8% of all instances of chronic-liver-disease-related deaths worldwide.

There at the moment exists no therapy for the long-term administration of NAFLD; nevertheless, dietary interventions have been investigated for the therapy of this illness, together with a number of polyphenolic compounds equivalent to ellagic acid.

ECU researcher Dr. Lois Balmer and Ph.D. scholar Mrs. Tharani Senavirathna famous that ellagic acid, which is present in quite a lot of meals equivalent to raspberries, pomegranate, blackberries, and pecan nuts, is widely known for its antioxidant properties, but in addition displays anti-inflammatory, antifibrotic and anticancer properties.

The paper is printed within the journal Antioxidants.

“Ellagic acid stands out as a exceptional polyphenolic compound, possessing a variety of pharmacological properties that maintain promise in treating numerous persistent ailments, together with NAFLD.

“As a result of its multifaceted organic results, edible vegetation containing ellagic acid, and its derivatives are acknowledged as helpful useful meals for enhancing human well being. Furthermore, there’s proof suggesting that ellagic acid, when mixed with different antioxidant nutraceuticals, displays a synergistic therapeutic impact, making it a possible candidate for mixture remedy.”

Mrs. Senavirathna was concerned in a beforehand undertaken pilot research investigating the consequences of a number of polyphenolic compounds on NAFLD, with ellagic acid displaying essentially the most promise in lowering irritation.

A bigger research is now underneath means which may also examine at which level of the sickness therapy can be ineffective to reverse harm to the liver.