Oral TRT Breakthrough! Dr. Cam Sepah Boosts Maximus Testosterone Protocol

An Oral TRT Breakthrough! Dr. Cameron Sepah of Maximus Joins PricePlow for Episode #127 to announce the upgrades to their Testosterone Protocol

0:00 – Introductions and the Huge Announcement

On Episode #127 of the PricePlow Podcast, Mike and Ben welcome Dr. Cam Sepah from Maximus again onto the present. Whereas this was recorded simply after Episode #124, which discusses the Maximus Blood Circulate Protocol (the “Prescription Pre-Exercise”), that is actually a follow-up to Episode #062, our unique introduction to Maximus and their groundbreaking enclomiphene drug.

The Maximus Testosterone Protocol Choices

In right this moment’s episode, Dr. Sepah discusses Maximus’ improvement of the primary oral testosterone substitute remedy (TRT) that’s non-suppressive, permitting people to keep up their pure testosterone manufacturing alongside supplementing with exogenous testosterone. He highlights the individuality of this remedy in comparison with conventional TRT and enclomiphene, a selective estrogen receptor modulator used for enhancing efficiency reasonably than treating extreme medical circumstances.

3:15 – Catching up on Enclomiphene

Dr. Sepah emphasizes Maximus’s method to well being and hormone optimization, which deviates from standard insurance-driven standards that limit TRT to these with severely low testosterone ranges.

To study extra about enclomiphene, the primary half of Dr. Sepah’s discovery, see Episode #062 or our major write-up titled “Is Enclomiphene the Testosterone-Enhancing Drug We’ve Been Wanting For?“.

8:00 – The Drawbacks of Conventional TRT

Dr. Cam critiques the standard TRT for its suppressive nature and potential unintended effects (together with destroying fertility in youthful customers who might want to have youngsters later in life), advocating for a extra nuanced and individualized method to hormone remedy. Dr. Sepah additionally touches on the historic challenges of making oral testosterone remedies as a consequence of points with liver toxicity and bioavailability, and the way the Oral TRT-enhanced model of the Maximus Testosterone Protocol works round these issues.

In Episode #062 of the PricePlow Podcast, we meet Dr. Cameron Sepah, founding father of Maximus, who’s right here that can assist you increase testosterone in a clinically-meaningful approach with out TRT. Put together to study a ton about enclomiphene on this episode… however what if customers need extra? Then it’s time for Episode #127, the place it’s mixed with new Oral TRT applied sciences!

This breakthrough remedy represents a shift in the direction of extra customized, efficient, and safer hormone optimization methods.

Dr. Sepah delves deeper into the problems with conventional TRT strategies, comparable to injectables inflicting spikes in testosterone ranges resulting in undesirable estrogenic unintended effects and the suppression of pure testosterone manufacturing. He highlights the advantages of newer oral testosterone formulations which can be absorbed by means of the lymphatic system, avoiding liver toxicity and sustaining extra secure testosterone ranges.

These formulations, nevertheless, have been costly as a consequence of patent protections.

11:45 – How Oral TRT Works

The answer to either side of the issue? He introduces a groundbreaking method combining oral testosterone with enclomiphene, a way that mitigates the suppressive results of TRT on pure hormone manufacturing, thus sustaining the physique’s skill to supply testosterone naturally. This progressive mixture remedy represents a major shift in the direction of simpler and safer hormone optimization methods, providing sufferers the advantages of enhanced testosterone ranges with out the drawbacks related to conventional TRT.

22:09 – Retaining the hormonal rhythm

Dr. Cam elaborates on the progressive mixture of oral testosterone substitute remedy (TRT) with enclomiphene, a selective estrogen receptor modulator (SERM), to create a synergistic impact that mitigates the suppressive results of testosterone on the physique’s pure hormone manufacturing. This mixture, distinctive to Maximus, ensures zero suppression of luteinizing hormone (LH), follicle-stimulating hormone (FSH), and neurosteroids, showcasing outstanding ends in medical trials. This method not solely elevates testosterone ranges considerably but additionally maintains the pure hormonal rhythm and steadiness with out inflicting dependence or tolerance.

Enclomiphene Citrate Mechanism of Motion. Picture courtesy Maximus Tribe

Dr. Cam discusses the sensible features of this remedy, together with the necessity for consumption with dietary fat for optimum absorption and the pliability in dosing schedules to go well with affected person preferences and existence. He highlights the pure pulsatile nature of hormone ranges and the way oral TRT, significantly in sync with pure rhythms, presents a extra bioidentical and fewer suppressive choice than conventional strategies.

30:15 – Misconceptions about enclomiphene

The Testosterone Protocol “v2” shall be provided alongside standalone enclomiphene and oral TRT choices – you don’t should go all-in for those who don’t need to. Dr. Sepah addresses misconceptions and scaremongering about enclomiphene, highlighting its security and efficacy based mostly on long-term knowledge and distinguishing it from Clomid as a consequence of its fewer unintended effects and extra focused motion.

He emphasizes the significance of customized dosing, managed by medical professionals, to attain optimum outcomes and decrease unintended effects. The dialogue additionally covers the importance of free testosterone over complete testosterone ranges in evaluating TRT efficacy and symptom enchancment, advocating for a nuanced understanding of hormone remedy past mere numerical targets.

41:25 – Administration mechanics – take with a fats supply

Enclomiphene: The Maximus Take a look at-Boosting Drug that may be a higher various to TRT

Dr. Sepah clarifies that the type of oral TRT used of their protocol is a strong pill, not an oil-based capsule, which tends to be extra gastrointestinal-friendly and lacks the “burp” impact related to oil-based capsules. He explains that when consumed with dietary fats, the pill’s contents are absorbed within the small gut after which by the lymphatic system, bypassing the liver’s first-pass metabolism, which permits the testosterone to retain its bioidentical kind with out alteration. This technique mimics the physique’s pure testosterone rhythm, avoiding the suppressive results seen with different TRT kinds.

He additionally discusses the customized dosing method, emphasizing the significance of adjusting dosages based mostly on particular person responses and outcomes. Sepah introduces an progressive at-home blood check that makes use of microneedle know-how for painless, correct testosterone stage monitoring, criticizing much less dependable salivary exams and highlighting the comfort and accuracy of their testing technique.

48:00 – Metabolism of oral testosterone… when’s the height?

Ben inquires concerning the pharmacokinetics of oral testosterone, significantly its peak results within the physique. Sepah emphasizes the person variability in drug metabolism however notes that, on common, oral testosterone peaks within the bloodstream inside three to 5 hours after ingestion. He re-emphasizes that the pill causes much less GI misery due to using the lymphatic system. This ends in a extra pure, bioidentical type of testosterone that mimics the physique’s personal manufacturing.

Dr. Cam additionally discusses the advantages of mixing oral testosterone with enclomiphene to mitigate the suppressive results of testosterone on the physique’s pure hormone manufacturing, making certain ranges don’t drop to zero however reasonably keep above baseline. He advises on dosing for optimum athletic efficiency, suggesting taking the treatment 4 hours earlier than exercise for peak results, whereas additionally stressing the significance of a constant, handy dosing schedule for long-term adherence over micromanaging timing for particular actions.

55:00 – The method of transitioning from injectable to oral TRT

Dr. Sepah addresses transitioning from injectable testosterone substitute remedy (TRT) to their oral TRT protocol. He explains that people taken with switching want to offer latest lab work or briefly stop their present TRT to ascertain baseline pure testosterone ranges. Sepah emphasizes the significance of understanding a person’s pure (“natty”) testosterone ranges to tailor the therapy successfully. The method includes a short interval off TRT to evaluate pure ranges, adopted by initiation into the oral TRT protocol, which can embody enclomiphene to stimulate pure testosterone manufacturing or act as a post-cycle remedy.

He discusses the advantages of oral TRT over injectables, comparable to much less gastrointestinal misery with strong tablets and a unique metabolic pathway that results in much less aromatization to estradiol, probably lowering the necessity for aromatase inhibitors. Sepah additionally mentions the potential unintended effects of upper DHT ranges related to oral TRT, like hair loss and zits, and suggests mitigating these with a 5-alpha reductase inhibitor like dutasteride or finasteride. This mixture not solely manages unintended effects however can also improve the testosterone impact.

1:08:00 – Customized method to hormone remedy

Maximus has a strong Discord Neighborhood

Ben and Dr. Sepah delve into the nuances of TRT and the broader spectrum of hormone optimization, highlighting the excellence between empirical, experience-based data (“bro science”) and misinformed hypothesis by “soy influencers.” Dr. Sepah defends the worth of bro science when it comes from aggressive athletes and bodybuilders who, by means of trial and error, have contributed invaluable insights into efficiency enhancement, comparable to using PDE5 inhibitors for muscle protein synthesis. He criticizes well being influencers who unfold misinformation with out firsthand expertise or scientific scrutiny.

The dialog shifts to the significance of nuanced, customized approaches in hormone remedy, emphasizing that what works for one particular person may not work for an additional. Dr. Sepah additionally touches on the complexity of hormone remedy, together with the totally different types of oral testosterone and techniques to handle potential unintended effects, advocating for knowledgeable, data-driven decision-making. He stresses the significance of long-form dialogue to totally perceive the intricacies of TRT and the person variability in response to therapy, difficult the oversimplification prevalent in on-line discourse.

1:15:15 – SHBG and IGF-1

Dr. Sepah delves into the affect of assorted components like intercourse hormone-binding globulin (SHBG) and insulin-like progress issue 1 (IGF-1) on hormone optimization. He explains that SHBG ranges are largely genetic and makes an attempt to chemically alter them are sometimes misguided. Sepah mentions that oral testosterone can naturally decrease SHBG ranges, enhancing free testosterone extra considerably than complete testosterone.

The Maximus Testosterone Protocol Merchandise

He additionally touches on the controversial matter of IGF-1, debunking the hype round progress hormone and its overrated results on muscle mass and restoration. Sepah criticizes the misinformation unfold by influencers and emphasizes the significance of nuanced, scientifically backed approaches to hormone remedy. He advocates for individualized therapy plans and highlights the evolving public notion and regulatory stance in the direction of TRT and hormone optimization therapies.

1:28:45 – Mike’s Hormone Panel

Mike, referring to his personal bloods, asks if this protocol can be indicated if somebody has excessive SHBG (intercourse hormone binding globulin, Dr. Cam says that is most likely genetic), common/good complete check, but low free check — and thus unable to placed on quite a lot of muscle. Dr. Sepah says if he doesn’t have any contraindications like a historical past of clotting problems, or being on blood thinners, then enclomiphene can be a very good answer.

For Mike, with free T of 97.8, he would seemingly see a pleasant increase as much as 150 and even 200. The primary good thing about this, in keeping with analysis, is elevated vitality. It’s not a jittery, caffeine-like vitality, however a peaceful vitality. Moreover, temper enhancements are widespread, although it isn’t marketed as a therapy for medical temper problems. Extra advantages embody work and athletic efficiency – with sufferers typically placing on as much as 5 kilos of lean muscle mass in 12 weeks, along with a pleasant energy increase.

Dr. Sepah goes on to say that if Mike took Oral TRT along with enclomiphene, the results can be much more pronounced, with a free T increase to over 200. Mike might see himself including enclomiphene sooner or later, and appreciates the brand new therapies obtainable for individuals to select from.

1:34:15 – Wrap Up

Mike and Ben specific appreciation for Dr. Sepah’s time, and Dr. SeCam notes how a lot he enjoys the science-based method that PricePlow takes in the direction of the complement aspect of issues. He emphasizes that the world wants good knowledge, and good science.

Ben notes that he want to strive the Oral TRT and Enclomiphene routine, and doc the outcomes. He has been on injectable TRT for a couple of years and want to see if the oral route is as efficient. Dr. Sepah thinks this regiment will find yourself being the best way nearly all of individuals take TRT as a result of comfort, fertility preservation, and extra.

For extra data, you may go to the Maximus web site, and you will discover Dr. Sepah on on social media within the hyperlinks beneath.