New 2024 Low-Stim Pre-Workout with EndoFlo, NeuroRush, and enfinity

One other nice product is right here with two Aura Scientific branded components — and extra!

Some manufacturers persist with the fundamentals. They construct their merchandise on the backs of established components. That’s positive for some, however with the intention to preserve the trade shifting forwards, we want manufacturers which might be prepared to pioneer promising new components – ones that may change the panorama of the trade as we all know it.

One model that’s been ambitiously pushing the brand new ingredient envelope is ProSupps. Final month, we coated ProSupps Thermo, a fats burner with two thrilling, novel components from Aura Scientific.

Thermo’s been unbelievable, however everyone knows that ProSupps’ actual magic is of their pre-workouts. And there aren’t any two names extra synonymous with epic pre-workouts than Jekyll and Hyde. And as we speak, the affair between ProSupps and Aura continues with the new-and-improved, lower-stim Jekyll Pre-Exercise:

ProSupps Jekyll: Up to date Decrease-Stim Pre with EndoFlo, NeuroRush, and enfinity

There’s a brand new ProSupps Jekyll components for 2024, and this lower-stim pre-workout is completely stacked with 4 of our favourite components, together with two newcomers from Aura Scientific, EndoFlo and NeuroRush!

In 2024’s Jekyll, we see some orthodox components like citrulline, betaine, and tyrosine. On high of those mainstays, we see EndoFlo from Aura, a botanical mix to spice up blood movement and circulation, enfinity paraxanthine as a easy stimulant choice, and NeuroRush, an intriguing espresso fruit extract, additionally from Aura.

This makes good sense, since Jekyll’s all the time been the lower-stimulant aspect of the two-faced Jekyll/Hyde combo. There’s no heavy-hitting caffeine dose, only a smoother nootropic duo of enfinity and NeuroRush — precisely what we’ve been anxiously ready for.

We’re going to dive into how ProSupps Jekyll works, however first, let’s test PricePlow for good ProSupps offers, and take a look at our video assessment of the brand new taste:

Notice: Search for the tubs with NeuroRush and EndoFlo on the labels. These new formulation are “Jekyll”, not “Dr. Jekyll”.

In comparison with the Hyde pre-workout line, Jekyll is a extra mellow choice for these not seeking to overdo it on stimulants. It’ll nonetheless provide you with a very good kick, but it surely’s easy and manageable.

ProSupps Jekyll Components

Every scoop (17.4g) of Jekyll incorporates the next components:

L-Citrulline (6000mg)

4 branded components within the 2024 ProSupps Jekyll

Citrulline, a conditionally important amino acid, enhances nitric oxide (NO) manufacturing,[1] which is essential throughout metabolic stress or intense coaching. Not like arginine, which is immediately concerned in NO manufacturing however is much less efficient supplementally because of the first cross impact in digestion, citrulline converts into arginine extra effectively, boosting blood arginine ranges.[2,3] This improved NO manufacturing leads to vasodilation, enhancing blood movement, oxygen, and nutrient supply to tissues whereas aiding within the elimination of metabolic byproducts, thereby enhancing athletic efficiency.[4-6]

Analysis signifies that citrulline supplementation can improve energy,[7] extend train endurance,[8] scale back muscle soreness,[8] increase progress hormone secretion,[9] reduce amino acid catabolism,[10] and promote muscle synthesis.[11,12]

Nice begin, however we will do much more for our pumps, each by way of hydration but in addition extra blood movement. Let’s get to a heavy hit of hydration first.

Betaine Anhydrous (4000mg)

You don’t want high-stim to have a great-feeling pre-workout.

Betaine, also called trimethylglycine (TMG), is an ergogenic assist that enhances mobile hydration and quite a few organic processes by donating methyl teams.[13] Because of these methyl teams, betaine helps the method of methylation, important for quite a few metabolic processes, together with managing homocysteine ranges, which, if elevated, pose a danger for cardiovascular ailments.[14]

Betaine’s potential to advertise mobile hyperhydration brings further glucose, oxygen, and vitamins into cells, growing resistance to emphasize.[15-17] Research have proven betaine’s effectiveness in enhancing energy, energy, and physique composition.[18-23] As an illustration, a 2013 examine discovered that day by day consumption of two.5 grams of betaine resulted in vital muscle achieve and fats loss,[15,24] with one other 2018 examine confirming comparable advantages in feminine athletes.[25]

These advantages clarify betaine’s rising reputation in sports activities dietary supplements. It’s powerful to discover a pre-workout with out it these days — however what we actually love right here is how ProSupps went above and past with a 4 gram dose, excess of the usual 2.5!

L-Tyrosine (2000mg)

Tyrosine enhances focus and cognitive operate by aiding the manufacturing of catecholamine neurotransmitters reminiscent of adrenaline and dopamine.[26-30] These neurotransmitters assist keep sharpness, alertness, and focus, that are essential for optimum efficiency throughout exercises.

Moreover, tyrosine can enhance the manufacturing of T3 and T4,[31,32] thyroid hormones vital for metabolic exercise.

Cognizin® (Citicoline) – 250mg

ProSupps Thermo is a brand new fats burning powder that guarantees power and urge for food management with thrilling new components like CapsiBurn and NeuroRush from Aura Scientific!

Choline, important for cell membrane construction and cognitive operate, is a precursor to acetylcholine, a neurotransmitter essential for studying and reminiscence.[33] Cognizin, a patented and trademarked type of citicoline (CDP-Choline), is superior to plain choline dietary supplements as a result of it promotes the manufacturing of acetylcholine and three key mind phospholipids: phosphatidylcholine, phosphatidylethanolamine, and phosphatidylserine.[34-36] These phospholipids are very important for cell membrane synthesis and mind well being.

Scientific research have proven that Cognizin enhances focus, consideration,[37-40] reminiscence,[41] and cognitive well being,[37,38,40,42] with vital enhancements noticed in visuospatial working reminiscence and episodic reminiscence in older adults.[41]

We’ve coated Cognizin quite a few occasions, and are all the time impressed by the quantity of analysis poured into the ingredient. To us, citicoline is the experiential type of choline — one that may be felt — with out overstimulation.

With a stable nootropic basis, it’s time to get again to blood movement.

EndoFlo™ – 150mg

EndoFlo, developed by Aura Scientific, is a proprietary mix of 4 botanical extracts designed to reinforce vasodilation and circulation. Let’s break every one down:

Mango [Mangifera Indica] Fruit Extract

Only one capsule brings some stable stimulant-free bolt-on pump results

First is Mangifera indica (mango fruit) extract, which has quite a few conventional makes use of,[43,44] together with supporting cardiovascular well being, which is all the time an important factor to see in a pump ingredient.

It’s most frequently standardized for the constituent mangiferin. This has vital phosphodiesterase 5 (PDE5) inhibiting exercise, resulting in elevated cyclic guanosine monophosphate (cGMP) ranges, and that interprets to easy muscle leisure, and improved blood movement.[45-49]

There’s even analysis on mango extracts demonstrating improved blood movement to the pores and skin[47,48] — not our precise use case, but it surely goes to point out how mangiferin-based extracts are so versatile and well being useful.

Mangiferin has a lot unbelievable analysis, there’s even a printed journal entry titled, “Mangiferin: a pure miracle bioactive compound towards way of life associated problems”.[50]

Mangiferin can be backed by an in depth quantity of security analysis.[51-56]

Black Ginger [Kaempferia parviflora] Root Extract

Not simply any ginger, that is black ginger — scientifically often called kaempferia parviflora. That is an especially versatile ingredient that helps helps vasodilation,[57-60] muscular endurance,[61,62] energy,[63,64] and adaptability.[65]

Essentially the most attention-grabbing a part of black ginger is one among its distinctive constituents, a bioactive flavonoid named 5,7-dimethoxyflavone (DMF). This has further cardioprotective, vasodilatory mechanisms that work by way of PDE5 inhibition.[66-68]

Two preclinical trials present that DMF are fairly anabolic, supporting energy positive factors,[63,64] and we stay up for human analysis to follow-up.

A brand new novel ingredient developer named Aura Scientific has launched, with 4 new components that embrace a feel-good coffeefruit extract named NeuroRush. Get the primary peak right here as we speak!

After wanting by way of the literature, there’s a very good probability that that is the key weapon in EndoFlo, however we’re not totally assured in stating that for the reason that different constituents are so helpful as effectively.

Ginkgo [Ginkgo biloba] Leaf Extract

Most complement customers know of ginkgo biloba, well-known as a memory-supporting nootropic assist. What most customers don’t know is that it really works by boosting cerebral blood movement,[69,70] additionally inhibits PDE5 and PDE4,[71] offering cardioprotective advantages!

So this isn’t only a nootropic ingredient, it’s additionally supportive of blood movement basically, which in fact goes to extra locations than simply the mind!

Pine [Pinus massoniana] Bark Extract

The least shocking constituent to see in EndoFlo is pine bark extract, as this has been used as a vasodilatory pump ingredient for many years now.

Pinus massoniana (pine bark) is wealthy in proanthocyanidins and antioxidants like catechin and epicatechin, which supply vital cardiovascular advantages.[72,73] It’s typically used to cut back vessel constriction,[72] so think about this a “defensive” ingredient to help the remainder of the components.

Enfinity Paraxanthine (150mg)

Usually, Jekyll offers a decrease caffeine dose compared to the high-caffeine dose with Hyde. In 2024, ProSupps did one thing even higher — they added enfinity!

Paraxanthine is among the major metabolites of caffeine and is liable for many of the useful results attributed to caffeine, reminiscent of fats burning,[74] adenosine inhibition,[75] dopamine upregulation,[76] and improved response occasions.[77]

Not like caffeine, which metabolizes into paraxanthine, theobromine, and theophylline, paraxanthine has a shorter half-life,[78,79] decreasing the unfavourable uncomfortable side effects like diminished sleep high quality related to the opposite metabolites.

There’s been lots of current analysis masking the advantages of paraxanthine, reminiscent of elevated power expenditure (~100 energy in 3 hours),[80] and higher enchancment in cognitive operate than caffeine after a 10km run.[81]

We’ve discovered that we will take paraxanthine later within the day, so that is good for many who use Jekyll as a pre-workout in late afternoons.

NeuroRush (100mg)

ProSupps finishes huge with one more Aura Scientific ingredient, this being one which we already noticed in ProSupps Thermo.

NeuroRush, a brand new espresso fruit extract from Aura Scientific, is standardized to include 50% chlorogenic acid in addition to 5-caffeoylquinic acid, giving it the prowess to dwell as much as its catchy identify. A 2019 examine demonstrated that 100 mg of espresso fruit extract can considerably scale back psychological fatigue and keep vigilance after demanding duties.[82]

Fast Assessment: It smells nice, and 100 milligrams prices issues up… however 200 milligrams is definitely intense!

Espresso fruit extracts are sometimes promoted for numerous advantages, particularly cognitive enhancements. Chlorogenic acid, the first bioactive constituent, is thought for its antioxidant and anti inflammatory properties,[83-85] which enhance cognitive efficiency and temper. Espresso fruit extracts additionally present potential pro-longevity results, supported by in depth analysis.[86-89]

Experiential with out overstimulation

One facet we notably recognize about chlorogenic acids is the optimistic approach they make us really feel – it really works nice in lower-stim pre-workouts as a result of it’s experiential. A 2019 examine highlighted espresso fruit extract’s “psychological energizing results” within the summary,[82] one thing we’re inclined to agree with — the ingredient anecdotally offers a way of “vitality.”

Moreover, two different research have proven that consuming drinks containing pure or supplemental chlorogenic acids can lead to rapid cognitive and temper enhancements.[83,84]

Curiously, a examine group that included a low dose of caffeine — simply 75 milligrams — reported vital optimistic temper results.[82] NeuroRush is flexible, working effectively in each highly-caffeinated and low-stim merchandise, and that’s why ProSupps has it each of their new fats burner and pre-workout.

Moreover, there’s wonderful security analysis on complete espresso fruit merchandise.[90] This class of components has earned our belief and appreciation, even with cautious complement customers.

You possibly can see the remainder of Aura Scientific’s secure in our article, “Aura Scientific: Novel Ingredient Developer Introduces 4 New Components“.

Added Nutritional vitamins and Minerals

Lastly, proSupps additionally certainly some stable nutritional vitamins and minerals, together with a pleasant dose of high-quality folate, which ought to go effectively with the vitamin B12:

Niacin (20 mg) – 125%
Folate (600 mcg as L-5-Methyltetrahydrofolate Calcium) – 250%
Vitamin B12 (400mcg as Methylcobalamin) – 16,667% DV
Pantothenic Acid (25mg) – 500% DV
Sodium (100mg as Sea Salt) – 4% DV
Potassium (115mg as Potassium Citrate) – 2% DV

All ProSupps Jekyll Flavors

The preliminary two flavors — however now we have a sense this product will succeed, and there shall be extra!

Jekyll will initially be out there in Strawberry Watermelon and Blackberry Lemonade. Take a look at our up-to-date listing of flavors under, however you’ll want to test the labels — there have been many variations of Dr. Jekyll through the years, however this one ought to simply say Jekyll with out the “Dr.”

Within the 2024 model, ProSupps can be proud to don’t have any FD&C dyes.

A New Period for Components

Corporations like Aura Scientific are bringing the complete weight of science to bear within the quest for brand spanking new performance-boosting compounds. With components like EndoFlo and NeuroRush, we will begin pushing the boundaries of what’s attainable. Although not from Aura, we’re additionally excited to see paraxanthine grace extra labels.

ProSupps Jekyll is a stable pre-workout – one which scratches that stimulant itch with out breaking pores and skin. For an on a regular basis, day by day driver choice, it’s a stable selection. Then, whenever you’re actually in want of a lift, you’ll be able to toss in a scoop of Hyde.

Notice: Search for the tubs with NeuroRush and EndoFlo on the labels. These new formulation are “Jekyll”, not “Dr. Jekyll”.