Kick Off 2025 with Applied Nutrition’s Fat Burning Supplements

As 2025 approaches, the not too long ago rebranded Utilized Vitamin USA (AN USA) enters the load administration class with Shred-X, launching in each capsule and powder type. This dual-format launch marks AN USA’s enlargement past their pre-workouts and sports activities efficiency merchandise, arriving simply in time for New Yr’s decision season.

Shred-X brings collectively acquainted substances like inexperienced tea extract, l-tyrosine, and l-theanine alongside B-vitamins to help vitality ranges and focus whereas weight-reduction plan. Whereas not a part of AN USA’s premium AN Efficiency Sequence, Shred-X supplies another choice for these beginning their 2025 health journeys with Utilized Vitamin.

The substances are barely completely different, with the powder offering extra bodily area, and this text will break all of them down.

Earlier than we get into the separate merchandise, get notified when AN USA launches new dietary supplements and flavors by signing up for our AN USA information alerts:

Each variations of Shred-X goal vitality, focus, and metabolic help, however take completely different approaches with their formulation.

The capsule model supplies a handy three-capsule serving with research-backed doses of inexperienced tea extract and caffeine, whereas the powder model leverages bigger doses of substances like acetyl L-carnitine (3 grams!) and betaine (1.5 grams) that merely wouldn’t match into capsules.

You’ll additionally discover distinctive substances in every model – the capsules embrace olive leaf extract whereas the powder accommodates Gymnema sylvestre and sweat-inducing GBB. We’ll analyze these variations as we discover every method beneath.

AN USA Shred-X Capsule Components

Every serving (3 capsules) accommodates:

Inexperienced Tea Extract (95% Polyphenols, containing 40% EGCG) – 400mg

The inspiration of Utilized Vitamin USA’s Shred-X method is a research-backed dose of inexperienced tea extract, standardized for catechins and EGCG (epigallocatechin gallate). Inexperienced tea extract has repeatedly demonstrated its effectiveness for supporting wholesome weight administration by way of a number of mechanisms of motion.

Inexperienced tea’s main bioactive compounds, significantly EGCG, work by inhibiting an enzyme referred to as catechol-O-methyltransferase (COMT).[1] This enzyme inhibition helps protect circulating catecholamines like norepinephrine, resulting in elevated thermogenesis and fats oxidation.

Analysis has proven that inexperienced tea extract can enhance each day vitality expenditure by roughly 4-5% and increase fats oxidation by 10-16% over 24 hours.[1] These results seem most pronounced when mixed with caffeine, as is completed within the Shred-X method.

Past its thermogenic properties, inexperienced tea extract supplies extra metabolic help by:

Enhancing insulin sensitivity and glucose metabolism[2]
Supporting wholesome lipid profiles[3]
Offering antioxidant advantages by way of its catechin content material[4]

The doses utilized in Shred-X (400mg capsules/450mg powder) align properly with quantities proven to be efficient in analysis, whereas staying properly beneath the higher restrict of 800mg EGCG per day thought-about secure for many wholesome adults.

Complete Caffeine – 200mg

The inspiration of Shred-X’s method is a reasonable 200mg dose of caffeine per serving, which is a tried-and-true ingredient for each vitality and fats loss help. Analysis has proven that caffeine can enhance metabolic charge and fats oxidation by way of a number of mechanisms, together with enhanced launch of fat-mobilizing hormones like epinephrine.[5]

Utilized Vitamin’s American Division is now AN USA, previously All Black Every thing (ABE). All Black Every thing is returning to its UK standing as a pre-workout.

In relation to weight administration, caffeine works primarily by inhibiting an enzyme referred to as phosphodiesterase, which helps break down cyclic AMP – a important molecule concerned in fats breakdown. By preserving cAMP ranges, caffeine can improve lipolysis (the breakdown of fats) and enhance fats oxidation, particularly throughout train.[6]

Past its fat-burning properties, caffeine is well-known for its means to spice up vitality ranges and application by blocking adenosine receptors within the mind. This not solely helps present the psychological vitality wanted to remain lively and centered throughout a food plan, however also can cut back the notion of effort throughout train, permitting you to coach more durable and longer.[7]

At 200mg per serving, Shred-X supplies an efficient however reasonable dose that almost all customers ought to tolerate properly. That is sufficient caffeine to help fats loss and vitality with out inflicting the jitters or anxiousness that may include larger doses. For context, that is roughly equal to 2 cups of espresso.

Cayenne Pepper Extract – 200mg

At 200mg, Shred-X features a reasonable dose of cayenne pepper extract to help its thermogenic properties. Cayenne pepper’s main bioactive compound is capsaicin, which analysis has proven will help enhance vitality expenditure and fats oxidation by way of a number of mechanisms.[8]

The thermogenic results of cayenne pepper are primarily mediated by way of activation of TRPV1 receptors, which may stimulate the sympathetic nervous system and enhance catecholamine launch.[9] This results in elevated vitality expenditure and enhanced fats oxidation, significantly in people with larger BMIs.[10]

Meta-analyses have proven that capsaicin supplementation can cut back vitality consumption by roughly 74 energy per meal[11] and enhance vitality expenditure by roughly 50 energy per day.[12]

Olive Leaf Extract – 200mg

Olive leaf extract (OLE) supplies one other fascinating angle to Shred-X’s method by way of its potent polyphenols, with oleuropein being the first lively compound.[13]

Analysis has proven that OLE will help help wholesome blood glucose administration and lipid metabolism. When mixed with a calorie-restricted food plan, OLE supplementation has been proven to beneficially influence physique weight and fats mass in comparison with food plan alone.[14]

The mechanisms behind OLE’s results seem like linked to its potent antioxidant properties and talent to help wholesome metabolic operate. Research point out that oleuropein and its spinoff hydroxytyrosol will help cut back lipid peroxidation and improve antioxidant enzyme exercise.[15]

At 200mg, Utilized Vitamin has included a reasonable however research-backed dose of OLE that ought to work synergistically with the opposite substances in Shred-X to help wholesome weight administration targets.

Choline Bitartrate – 183mg (offering 75mg choline, 14percentDV)

At 183mg of choline bitartrate (offering 75mg choline), we’ve got a reasonable however helpful dose that may help a number of pathways helpful throughout a food plan. Whereas this isn’t a large quantity, choline performs necessary roles in fats metabolism and cognitive operate that shouldn’t be missed.

As a vital nutrient, choline serves as a constructing block for phosphatidylcholine, a important phospholipid concerned in fats transport and metabolism.[16] That is particularly related throughout weight reduction efforts, as correct fats metabolism turns into more and more necessary when in a caloric deficit.

Moreover, choline helps help the manufacturing of acetylcholine, typically referred to as the “studying neurotransmitter”, which will help keep psychological readability and focus throughout low-calorie intervals.[17] Analysis has additionally proven that choline supplementation could assist enhance carnitine retention in muscle tissue, doubtlessly supporting fats utilization throughout train.[18]

L-Tyrosine – 150mg

At 150mg of L-tyrosine, Utilized Vitamin features a modest dose to help temper and focus throughout weight-reduction plan phases. Whereas this isn’t a clinically-supported dose, it could nonetheless contribute to the method’s general results, particularly when mixed with caffeine.

L-tyrosine serves as a important precursor to dopamine and norepinephrine – key neurotransmitters that help focus, motivation, and cognitive efficiency.[19] That is related throughout calorie-restriction, when mind catecholamine ranges could also be affected by dietary modifications.

Analysis reveals that tyrosine supplementation will help keep optimum catecholamine ranges throughout anxious circumstances.[20] Whereas most research use larger doses, even modest quantities of tyrosine could assist help some psychological readability and focus throughout a food plan, particularly when paired with the method’s caffeine and different nootropic substances.

L-Theanine – 150mg

L-Theanine is an amino acid discovered naturally in tea leaves that works synergistically with caffeine whereas serving to to cut back potential jittery unwanted side effects. This “sensible caffeine” mixture is especially helpful in a high-energy method like Shred-X.[21]

L-theanine achieves this by selling rest with out sedation by way of its results on mind wave exercise and neurotransmitter operate.[22] Analysis reveals it could assist cut back anxiousness and stress whereas sustaining alertness.[23]

At 150mg alongside 200mg complete caffeine, Shred-X supplies a ratio that will assist customers keep focus and productiveness whereas minimizing the “crash” typically related to high-stim formulation.[24]

Theacrine – 50mg

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Theacrine is a naturally-occurring compound structurally just like caffeine, discovered primarily in Camellia kucha tea leaves.[25] Like caffeine, theacrine works by way of a number of mechanisms, together with adenosine receptor antagonism and phosphodiesterase inhibition, which will help improve vitality, focus, and motivation.[26]

What makes theacrine significantly fascinating is that not like caffeine, analysis suggests customers could not develop tolerance to its results with continued use.[25] In efficiency research, theacrine has demonstrated spectacular outcomes, with one research exhibiting enhancements of 27-38% in time to exhaustion throughout train.[27]

At 50mg, Shred-X supplies a reasonable dose that works synergistically with its caffeine to help sustained vitality and focus throughout weight reduction efforts, however observe that some analysis is confounded with extra substances that aren’t on this method.[28-30]

Acetyl L-Carnitine – 25mg

The powder model of Shred-X accommodates a considerable 3 gram dose of Acetyl L-Carnitine (ALCAR), whereas the capsule model consists of simply 25mg – a major distinction between the 2 formulation that closely favors the powder for this ingredient’s advantages.

ALCAR is the acetylated type of L-carnitine that’s believed to extra simply crosses the blood-brain barrier in comparison with commonplace L-carnitine.[31] This enhanced bioavailability permits ALCAR to help each bodily and cognitive advantages throughout a weight reduction section.

Utilized Vitamin USA shakes up the pre-workout recreation with AN Efficiency PRE! That includes Cognizin citicoline, NeuroRush, pure caffeine, and Knowledgeable Sport certification, it delivers vitality, focus, and efficiency you may belief.

When it comes to fats loss help, ALCAR helps transport long-chain fatty acids into the mitochondria the place they are often oxidized for vitality.[31] This transport system is particularly necessary throughout caloric restriction when optimizing fats utilization turns into essential.

The three gram dose within the powder model aligns properly with scientific analysis exhibiting enhancements in fats oxidation and train restoration.[32] Whereas the 25mg within the capsules is probably going too low to supply significant advantages by itself, the powder model supplies a research-backed dose that will:[33]

Improve fatty acid oxidation throughout train
Help train restoration and cut back muscle soreness
Assist keep psychological vitality and focus throughout caloric restriction

The dramatic distinction in ALCAR content material between formulation is among the key differentiating elements that will affect which model shoppers select, with the powder providing considerably extra potential for enhanced fats oxidation and train restoration help.

Nutritional vitamins and Minerals:

Vitamin B3 (as Niacinamide) – 16mg (100% DV)

Vitamin B6 (as Pyridoxine HCl) – 5mg (294% DV)

Vitamin B12 – 200mcg (8333% DV)

Chromium Picolinate – 116mcg (offering 14.4mcg chromium, 41% DV)

AN USA Shred-X Powder Components

Every serving (1 scoop / 10g) accommodates:

Acetyl L-Carnitine – 3g

See above, however observe that this can be a far better dose!

Betaine Anhydrous – 1.5g

Betaine (trimethylglycine) serves a number of roles within the method by way of its capabilities as each an osmolyte and methyl donor. At 1.5 grams, AN USA supplies a reasonable however nonetheless doubtlessly helpful dose, though most profitable scientific research use 2.5 grams per day.[34]

Analysis signifies betaine could help physique composition enhancements when mixed with resistance coaching by selling favorable modifications in muscle mass and fats loss.[35] It could additionally improve energy output and work capability throughout high-volume resistance coaching.[36]

Whereas the 1.5 gram dose is decrease than what’s sometimes studied, it might nonetheless contribute to the method’s general effectiveness, particularly when mixed with different substances that help physique composition and efficiency.

Inexperienced Tea Extract – 450mg

See above.

Choline – 300mg

See above.

Gymnema Sylvestre Extract – 250mg

Gymnema sylvestre is an herb historically utilized in Ayurvedic medication that has gained consideration for its results on sugar cravings and glucose metabolism. The lively compounds in Gymnema, often called gymnemic acids, can quickly block candy style receptors on the tongue, doubtlessly lowering cravings for sugary meals.[37]

Analysis suggests Gymnema could assist help wholesome blood sugar ranges by way of a number of mechanisms, together with enhanced insulin secretion and decreased glucose absorption within the intestines.[38]

At 250mg, Shred-X supplies a reasonable dose that will assist cut back sugar cravings whereas weight-reduction plan, although larger doses are sometimes utilized in analysis analyzing its results on blood glucose administration.[39]

L-Theanine – 250mg

See above.

L-Tyrosine – 250mg

See above.

Taurine – 250mg

Taurine is a conditionally important amino acid that’s discovered abundantly in muscle tissue and serves a number of capabilities together with osmoregulation, antioxidant protection, and calcium signaling modulation.[40]

When it comes to train efficiency, taurine has been proven to enhance endurance and cut back fatigue, though these advantages are sometimes seen at larger doses (1-6g).[41]

Whereas the 250mg dose in Shred-X is on the decrease finish, taurine should still present modest help throughout calorie-restricted phases by serving to keep mobile hydration and aiding with mobile vitality manufacturing.[42]

Caffeine Anhydrous – 200mg

See above.

Gamma-butyrobetaine Ethyl Ester Chloride – 30mg

Utilized Vitamin lastly features a strong dose of gamma-butyrobetaine (GBB), which serves because the direct precursor to L-carnitine within the physique’s pure carnitine manufacturing pathway.[43]

What makes GBB significantly fascinating is its pronounced thermogenic impact that manifests as elevated sweating throughout train. This impact was first documented when researchers needed to cut back doses in early research as a result of members reported extreme sweating at larger doses.

Past the sweating response, analysis has proven that GBB supplementation can considerably enhance plasma carnitine concentrations – serving to optimize fats transport and utilization.[43]

At 30mg, Shred-X supplies an efficient dose that will help each carnitine manufacturing and thermogenesis with out inflicting excessive sweating that may happen at larger doses. Simply bear in mind to deliver a towel to the health club!

Nutritional vitamins and Minerals

Vitamin B3 (as Niacinamide) – 25mg (156% DV)

Vitamin B6 (Pyridoxine Hydrochloride) – 5mg (294% DV)

Vitamin B12 (Cyanocobalamin) – 100mcg (4166% DV)

Vitamin C (L-Ascorbic Acid) – 1000mg (1111% DV)

Wanting on the formulation facet by facet like this, we will see that the powder has considerably extra lively substances like acetyl L-carnitine, and consists of extra substances like betaine, taurine, and GBB that aren’t within the capsule model.

Shred-X Powder Flavors Out there

Right here’s an up-to-date listing of all flavors of AN USA Shred-X powder:

Dosage and Timing

For the capsule model, AN USA recommends taking 3 capsules within the morning with meals. To evaluate tolerance, begin with a single capsule and regularly enhance the dose.

For the powder model, combine 1 stage scoop (10g) with ~7oz chilly water and drink within the morning or quarter-hour previous to train. As with all complement containing stimulants, begin with a half scoop to guage your tolerance.

To keep up effectiveness, take into account biking off after 8 weeks of steady use. Don’t exceed 1 serving per day of both model.

Facet Results and Warnings

As a result of caffeine content material in each variations, keep away from taking Shred-X inside 4-6 hours of bedtime. Don’t mix with AN Efficiency PRE or different stimulant-containing dietary supplements. When you’re trying to stack this with a pre-workout, think about using AN Efficiency‘s stimulant-free model as an alternative.

Moreover:

Don’t use if pregnant or nursing
Seek the advice of a healthcare skilled earlier than use you probably have any medical circumstances
Discontinue use and seek the advice of your physician for those who expertise any antagonistic reactions
Don’t exceed advisable serving dimension
Preserve out of attain of kids

Once more, these delicate to caffeine or different stimulants ought to begin with a decreased serving dimension to evaluate tolerance.

Conclusion: Beginning 2025 with AN USA

Aaron Heidebreicht is the brand new CEO of Utilized Vitamin’s US division. He defined his plans in Episode #130 of the PricePlow Podcast.

Whereas Shred-X could not characteristic novel substances or breakthrough know-how like AN USA’s premium AN Efficiency line that we helped formulate (Shred-X was made by the UK staff), it represents one other step within the firm’s rising American presence. The twin-format strategy provides customers flexibility in how they strategy their 2025 weight administration targets, whether or not they want the comfort of capsules or the flexibility of a powder.

As mentioned in our current podcast with AN USA CEO Aaron Heidebreicht, the corporate continues to broaden thoughtfully into new classes whereas sustaining their dedication to high quality manufacturing requirements. For these starting their New Yr’s health journey, Shred-X supplies an easy possibility to enhance AN USA’s present lineup of sports activities vitamin merchandise.