Dietary vitamin E may be protective against atopic dermatitis

Dietary consumption of vitamin E might doubtlessly decrease the danger for atopic dermatitis, in line with a examine revealed on-line Aug. 9 in Pores and skin Analysis & Expertise.

Siqing Wang, from the Beijing College of Chinese language Medication, and colleagues carried out a Mendelian randomization evaluation to discover the causal relationship between dietary antioxidant vitamin consumption (vitamin C, vitamin E, carotene, and retinol) and atopic dermatitis.

The researchers noticed a causal relationship between vitamin E consumption and atopic dermatitis (odds ratio, 0.859; 95% confidence interval, 0.745 to 0.992; P = 0.038). No causal relationship was seen between the opposite three nutritional vitamins and atopic dermatitis (odds ratios [95% confidence intervals], 0.953 [0.826 to 1.099; P = 0.507], 1.011 [0.864 to 1.184; P = 0.890], and 1.063 [0.893 to 1.264; P = 0.492] for vitamin C, carotene, and retinol, respectively). In a sensitivity evaluation, not one of the single-nucleotide polymorphisms had been detected as heterogeneous and no vital pleiotropy was noticed.

“The evaluation means that dietary consumption of vitamin E might doubtlessly cut back the danger of atopic dermatitis. Conversely, consumption of vitamin C, retinol, and carotene doesn’t look like causally associated to atopic dermatitis,” the authors write. “Though vitamin E consumption might be protecting towards atopic dermatitis, consumption of dietary antioxidant nutritional vitamins to stop or deal with atopic dermatitis will not be needed.”

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