On Episode #147 of the PricePlow Podcast, Mike and Ben are joined by Eric Withee, the Director of Ingredient Innovation at Freemen Nutra. The highest of dialog is a brand new dietary complement ingredient named Digexin, which is a mixture of ashwagandha and okra extracts designed to help intestine well being.
Freemen Nutra is historically a distributor of commodity elements, however is now starting to give attention to branded, research-backed elements to remain forward within the trade, they usually’ve acquired a star in Digexin. This ingredient promotes peristalsis — contraction of clean muscle within the intestine, serving to to facilitate the motion of meals.
This finally results in dramatically improved bowel actions, however as the info reveals, a lot extra.
The trio get into the gut-brain axis, an rising area of analysis that we’re solely starting to know, however hasn’t been correctly focused by the dietary complement trade — till the event of Digexin.
That is an attention-grabbing ingredient that feels good, and has terribly spectacular information within the two randomized managed trials which were performed up to now. They’re each mentioned under, in addition to in our principal Digexin article, so let’s dive in:
0:00 – Introductions
On Episode #147 of the PricePlow Podcast, Mike interviews Eric Withee, the Director of Ingredient Innovation at Freemen Nutra, a couple of new dietary complement ingredient known as Digexin. Freemen Nutra, historically a distributor of commodity elements, is now specializing in branded, research-backed elements to remain forward within the trade. Digexin, their newest innovation, is a proprietary mix of ashwagandha and okra extracts designed to advertise peristalsis—the contractions of clean muscle within the intestine that facilitate the motion of meals.
The mix of those extracts reveals a synergistic impact, requiring fewer items to induce peristalsis in comparison with every extract used alone. Eric explains that this wholesome contraction is important not just for stopping constipation but additionally for guaranteeing correct digestion and meals motion by the small gut, thereby stopping stagnation and related digestive points.
4:15 – Digexin
Eric explains that Digexin, a mix of ashwagandha and okra, has proven promising leads to preclinical and medical research, primarily focusing on constipation by enhanced peristalsis. Nevertheless, the complement additionally displays broader advantages for the whole gastrointestinal (GI) tract, together with reduction from reflux, bloating, stomach ache, and indigestion.
These results counsel that Digexin not solely aids bodily intestine capabilities but additionally impacts the gut-brain axis by decreasing stress, anxiousness, and bettering sleep, which may affect GI well being. This twin mechanism—enhancing each intestine motility and psychological leisure—aligns with the up to date tips from the American Gastroenterological Affiliation, which emphasize the significance of contemplating psychosocial components in managing GI problems.
12:00 – The Intestine-Mind Axis
Mike and Eric talk about the connection between stress, bowel actions, and the gut-brain axis, specializing in whether or not improved bowel actions can scale back stress or if lowered stress can facilitate bowel actions. They describe this interplay as a optimistic suggestions loop, the place Digexin aids each intestine well being and stress discount, enhancing general digestive operate.
Eric explains that Digexin’s twin motion, selling peristalsis and decreasing stress, helps each fast and long-term digestive well being. He notes that the extraction course of for the ashwagandha and okra in Digexin is exclusive, differentiating it from different merchandise. The dialog additionally touches on the hormone gastrin, which prepares the digestive system for meals, and discusses optimum bowel motion frequency, highlighting that whereas particular person wants differ, a median of 1 per day is mostly thought of wholesome.
19:00 – The Uniqueness of Digexin
Eric discusses the individuality of Digexin within the realm of intestine well being dietary supplements. Eric explains that Digexin is probably going the primary ingredient particularly researched to work from the mind to the intestine, serving to with each psychological leisure and gastrointestinal (GI) points. Not like widespread intestine well being dietary supplements like fibers, prebiotics, and probiotics, which primarily have an effect on the intestine and have downstream results on different physique elements, Digexin addresses the gut-brain axis by selling psychological leisure, which will help alleviate GI signs.
Eric emphasizes that whereas Digexin isn’t a alternative for fibers—necessary for general GI wellness and coronary heart well being—it enhances conventional intestine well being approaches by addressing psychological components that usually contribute to digestive issues. He notes that whereas fiber is likely to be satisfactory for short-term dietary deficiencies, many GI points are extra advanced and require a holistic method that features managing stress and psychological well being.
23:45 – The World of Intestine Issues
Ben and Eric talk about the complexity of intestine well being and the problem of making a single complement that addresses numerous intestine points. They spotlight the broad spectrum of intestine well being issues, from microbiome composition to gastrointestinal (GI) problems like constipation, bloating, and acid reflux disorder. Eric factors out that whereas many dietary supplements goal particular elements of intestine well being, Digexin is exclusive in addressing the gut-brain axis, serving to alleviate each bodily GI signs and stress-related points.
Eric outlines two principal shopper profiles for Digexin: people with power intestine points exacerbated by stress, and high-stress people whose GI issues stem from their psychological state. For every, a tailor-made method combining Digexin with different dietary supplements like anti-inflammatory brokers or calming minerals might be efficient.
31:45 – Digexin’s Versatility and Spectacular Information
Mike and Eric talk about the potential versatility of Digexin, highlighting its spectacular leads to medical research for bettering intestine well being, sleep high quality, and general well-being.[1] Mike notes the numerous enhancements in signs like stomach ache, constipation, diarrhea, indigestion, and reflux, emphasizing that Digexin supplies a balanced impact quite than merely addressing one challenge on the expense of one other.[2]
In addition they discover the potential of Digexin as an ingredient in numerous kinds of dietary supplements past intestine well being, resembling sleep aids, attributable to its optimistic influence on sleep metrics like decreasing time to go to sleep and bettering sleep high quality. The dialog underscores Digexin’s potential as a holistic complement, helpful for each bodily and psychological well being, and the technique of incorporating it into numerous formulations to maximise its attain and effectiveness.
37:45 – Constipation
Mike, Eric, and Ben talk about the significance of addressing constipation and different gastrointestinal (GI) problems, emphasizing that these situations considerably influence high quality of life. Mike highlights that standard remedies, like irritant laxatives, work by aggressively stimulating the intestine, which isn’t a sustainable resolution. Eric notes that practical GI problems, together with situations like IBS,[3] have an effect on a good portion of the U.S. inhabitants and infrequently end in a high quality of life worse than that of people with extreme sicknesses resembling end-stage renal illness or diabetes.
The section underscores the necessity for higher consciousness and open dialogue about bowel well being, as managing waste elimination from the physique is essential for general well-being. They counsel that society ought to normalize conversations about digestive well being, as it’s a elementary side of sustaining good well being and managing toxicity.
42:00 – First Digexin Complement: Well being Via Vitamin’s Aware GI
The group highlights the primary industrial product incorporating Digexin, Aware GI by Well being By Vitamin, which mixes Digexin with different gut-supportive elements like magnesium bisglycinate and glutamine. They talk about the product’s formulation technique, emphasizing its potential in addressing constipation and selling general digestive well being.
46:00 – Different Freemen Nutra Branded Components: MemoQ and TamaFlex
Eric shares insights into Freemen Nutra’s method to figuring out and creating branded elements, specializing in discovering companions with robust scientific backgrounds to commercialize revolutionary merchandise. He mentions different elements like MemoQ, a nootropic, and Tamaflex, a joint well being product, illustrating Freemen Nutra’s numerous portfolio. The dialog additionally touches in the marketplace’s want for efficient, well-researched elements, particularly in area of interest classes like ladies’s well being.
48:00 – Sourcing Components
Mike and Eric talk about Freemen Nutra’s present method to sourcing new elements. Eric explains that they’re in a “pull” mode, specializing in consolidating their current portfolio and guaranteeing inner readiness quite than actively searching for new elements. He emphasizes the significance of inner coaching and system setup to help their present choices. In addition they contact on the challenges and methods in advertising elements for particular demographics, resembling ladies’s well being.
Eric means that conducting focused analysis research, like these specializing in ladies, may enable corporations to make particular well being claims and differentiate their merchandise. They agree that whereas weight-reduction plan and vitamin are elementary to well being, dietary supplements can play a supporting function, supplied they’re marketed and utilized appropriately.
52:15 – Goodbyes
Mike expresses his appreciation for the insightful dialogue, stating that he gained extra concepts than anticipated, particularly relating to Digexin and its potential makes use of. Each Mike and Ben reward Eric Withee for sharing his experience, with Ben mentioning his optimistic expertise utilizing a product containing Digexin. They talk about how listeners can be taught extra or get in contact, directing them to Freemen Nutra’s LinkedIn web page and offering an electronic mail tackle for inquiries. The dialog wraps up with mutual thanks and enthusiasm for the information shared through the podcast.
Thanks to Eric for becoming a member of us, and to everybody for listening and following alongside!