In Episode 140 of the PricePlow Podcast, we’re joined by Dr. Barrie Tan, founding father of American River Vitamin, for an in-depth dialogue concerning the highly effective nutrient geranylgeraniol (GG, bought as GG-Gold) and its wide-ranging well being advantages – particularly with respect to muscle.
Dr. Barrie Tan, founding father of Amerian River Vitamin, joins The PricePlow Podcast #140 to clarify how GG-Gold (Geranylgeraniol) Helps Muscle Tissue!
Dr. Tan, a famend knowledgeable within the subject of phytonutrients and the world’s authority on vitamin E, brings a wealth of information and expertise to the desk, sharing insights from his in depth analysis on GG and different crucial compounds. This episode presents listeners a sound understanding of GG’s position in human biochemistry, highlighting its significance as a constructing block for varied organic processes and hormones.
The dialog begins with a quick introduction of Dr. Tan’s schooling and early analysis, adopted by his profession transition from academia to entrepreneurship — however he by no means stopped conducting and publishing analysis. All of it started when he was learning the enormous marigold flower (for eye well being), which serendipitously led to the invention of the annatto plant and its distinctive compounds, together with tocotrienol, a lesser-known however potent type of vitamin E — and finally, GG.
The crucial features of geranylgeraniol (GG) within the human physique
All through the episode, Dr. Tan explores the crucial features of GG within the physique, emphasizing its position within the synthesis of important compounds resembling CoQ10 and vitamin K2. He explains how GG helps muscle synthesis by aiding within the formation of skeletal muscle proteins and underscores the significance of sustaining ample GG ranges, particularly as we age. The dialogue additionally touches on the influence of statin medication on GG manufacturing and the following results on muscle well being and vitality ranges, highlighting the potential advantages of GG supplementation in mitigating these unwanted effects.
Join PricePlow’s American River Vitamin information alerts
Because the dialog progresses, Dr. Tan explains the sensible purposes of GG supplementation, together with its synergistic results when mixed with different vitamins like CoQ10 and Vitamin K2. He supplies beneficial insights into really useful dosages and the holistic advantages of utilizing pure, endogenous vitamins to assist total well being. The episode concludes with a stunning sizzling tackle a sure mineral that he thinks we could get an excessive amount of of.
Whether or not you’re a well being fanatic, an athlete, or just curious concerning the newest developments in dietary science, this episode is filled with beneficial data and sensible recommendation, and Dr. Tan is solely a enjoyable speaker to hearken to.
This one’s greatest watched on YouTube (under), as Dr. Tan reveals a couple of examples, however you may as well hear on iTunes, Spotify, or any RSS-enabled podcast app.
Subscribe to the PricePlow Podcast on Your Favourite Service (RSS)
YouTube
https://weblog.priceplow.com/podcast/barrie-tan-gg-gold-muscle-140
Video: Watch Dr. Barrie Tan Focus on GG-Gold
Podcast: Play in new window | Obtain (Length: 1:01:29 — 61.0MB)
Present Notes with Dr. Barrie Tan – GG-Gold for Muscle!
0:00 – Introduction and Dr. Barrie Tan’s Background
5:00 – Discovering Geranylgeraniol (GG)
Dr. Tan discusses his discovery of geranylgeraniol (GG) whereas researching tocotrienol from the annatto plant.
He explains the importance of GG in each plant and human biochemistry.
Geranylgeraniol (GG), bought as GG-Gold by Dr. Barrie Tan’s American River Vitamin, is a vital nutrient that’s used as a side-chain in Vitamin K2 and is crucial for organic features together with CoQ10 (Coenzyme Q10) manufacturing, testosterone, muscle mass, bone well being, intestine well being, and extra!
GG is highlighted as a crucial constructing block in varied organic processes, together with the synthesis of vital compounds in vegetation like chlorophyll and carotenoids, and in people, resembling purple blood cell manufacturing, muscle synthesis, and the formation of CoQ10 (Coenzyme Q10) and vitamin K2.
Dr. Tan elaborates on the position of GG as a vital part within the biosynthesis of those essential compounds, emphasizing its significance for total well being.
10:00 – GG’s Function in Vegetation and People
Dr. Tan supplies an in depth clarification of GG’s position within the synthesis of vital compounds in vegetation, resembling chlorophyll and carotenoids.
He emphasizes the essential features of GG in people, together with purple blood cell manufacturing, muscle synthesis, and the formation of CoQ10 and vitamin K2.
GG is described as a constructing block vital for varied biochemical processes in each vegetation and animals.
Dr. Tan highlights the importance of GG in sustaining total well being and its potential advantages when supplemented.
As a result of Geranylgeraniol participates within the mevalonate pathway, it performs an vital position in the complete organic world – it’s current and utilized in a molecular constructing block in each prokaryotic and eukaryotic organisms.[2]
15:00 – How Geranylgeraniol Helps Muscle Protein Synthesis
Dr. Tan explains how GG helps muscle protein synthesis by aiding within the formation of skeletal muscle proteins.
He makes use of the analogy of GG performing as an adjunct that helps sew amino acids collectively to kind proteins.
The dialogue consists of the significance of GG in muscle well being and restoration, significantly as folks age and GG ranges decline.
Dr. Tan mentions that GG ranges may be affected by statin medication, which may inhibit GG manufacturing and influence muscle well being.[3] GG considerably decreases statin-induced muscular weak spot in animals.[4,5]
20:00 – The Impression of Ageing and Statins on GG Ranges
The dialog focuses on how GG ranges decline with age — and the influence of statin medication on GG and CoQ10 ranges.
Dr. Tan explains the mechanism of statins inhibiting GG manufacturing and the following results on muscle well being and vitality ranges. This is named statin-associated muscle signs (SAMS), which ends up in quite a few detrimental results on the physique.[6]
Muscle mass from Geranylgeraniol-treated rats (GG), significantly the gastrocnemius, had been capable of generate extra drive than muscle mass from non-GG-treated animals.[4]
As mentioned in our foremost geranylgeraniol article, a meta-analysis confirmed that CoQ10 doesn’t at all times forestall SAMS,[7] however GG does![2]
He discusses the significance of sustaining ample GG ranges for total well being, significantly for people on statin medicines.
Dr. Tan highlights the potential advantages of GG supplementation in mitigating the unwanted effects of statins, resembling muscle ache and fatigue.
25:00 – GG Supplementation and Its Advantages
30:00 – GG and Testosterone Manufacturing
As a small-molecule constructing block,[2] this leads our dialog into testosterone.
Dr. Tan supplies insights into how GG supplementation can assist testosterone manufacturing — we’ve seen this in cells,[8] animals,[9] and males.[10]
He shares outcomes from medical research exhibiting a strong 20% enhance in testosterone ranges with GG supplementation.[10]
The dialogue consists of the holistic advantages of GG as an endogenous nutrient that helps total well being, past simply boosting testosterone ranges.
Dr. Tan highlights the significance of utilizing pure, endogenous vitamins like GG for well being and wellness, somewhat than relying solely on exogenous compounds. “No one has a tongkat ali deficiency!” Mike factors out that that is an ingredient that can be utilized by anybody, whether or not or not they’re utilizing exogenous hormones.
35:00 – The Function of MK4 and Bone Well being
Dr. Tan explains how GG is important for the manufacturing of MK4, a type of vitamin K2,[11,12] and its position in selling bone well being and stopping vascular calcification. GG inhibits osteoclast formation.[13] Analysis additionally reveals that statins, which deplete GG, additionally deplete the physique’s endogenous K2 manufacturing![14]
The chemical construction of Geranylgeraniol (GG), vs. that of MK-4 (vitamin K2).[15] As you may see, GG accounts for a big a part of the MK-4 molecule.
He emphasizes the interconnectedness of muscle and bone well being, highlighting the significance of each myogenic (muscle-building) and osteogenic (bone-building) processes.
The dialogue consists of how MK4 helps in calcium transport, making certain correct calcium distribution within the physique, and stopping calcification in mushy tissues, arteries, and joints.
Dr. Tan supplies sensible recommendation on combining GG with MK4 supplementation for optimum bone and muscle well being. Though the GG molecule is used to make vitamin Ok, it’s nonetheless not a substitute — it’s greatest to make use of them collectively.
40:00 – Sensible Functions and Complement Suggestions
45:00 – Questions and Future Analysis
Dr. Tan solutions questions on GG and ongoing analysis.
He discusses potential new findings and future research associated to GG and its purposes in well being and wellness.
The dialog touches on the significance of continued analysis to totally perceive the scope of GG’s advantages and its potential in varied well being situations.
Dr. Tan highlights a few of the thrilling future instructions for GG analysis and potential new product developments.
50:00 – Calcification and An excessive amount of Calcium?
Mike factors out that Dr. Tan’s mentioned calcium in fairly a destructive gentle, resulting from calcification, which vitamin K2 and GG can fight in opposition to (side-note: calcification is thought to be attributable to extra Vitamin A and Vitamin D3,[16-23] one thing to concentrate on in case your joints/bones are hurting). So he asks — do we actually must exit of our approach to get extra calcium?
The reply is definitely stunning — Dr. Barrie believes that our calcium RDA is simply too excessive! That is undoubtedly one thing to think about when placing a heart-healthy, joint-friendly weight-reduction plan collectively.
55:00 – Closing Remarks and Contact Info
Dr. Tan supplies remaining ideas on the significance of GG and vitamin E.
Info on the place to observe Dr. Tan and American River Vitamin for updates on new analysis and product releases.
Dr. Tan mentions his upcoming e-book on vitamin Ok and its significance.
They supply data on the place listeners can discover extra content material associated to GG and vitamin E, in addition to upcoming episodes.
Mike mentions the hyperlink to the PricePlow Weblog submit on GG-Gold and encourages listeners to test it out for extra detailed data and references. As an illustration, we didn’t actually get into the intestine microbiome research,[24,25] which might have taken the dialog to an entire totally different space.
Last reminders for listeners to subscribe, go away opinions, and observe PricePlow on social media for the most recent updates.
Mike and Ben thank Dr. Tan for his insights and encourage listeners to remain tuned for extra updates and future episodes – contact hyperlinks are under!
The place to Discover Dr. Barrie and American River Vitamin
Due to Dr. Barrie for becoming a member of us and explaining some biochemistry in a manner that every one of us can perceive.
Subscribe to the PricePlow Podcast in your favourite platform, and please go away us a evaluation on iTunes and Spotify!
Subscribe to the PricePlow Podcast on Your Favourite Service (RSS)
YouTube
Designs For Well being Annatto-GG 300 – Offers and Value Drop Alerts
Get Value Alerts
No spam, no scams.
Disclosure: PricePlow depends on pricing from shops with which now we have a enterprise relationship. We work laborious to maintain pricing present, however you might discover a higher supply.
Posts are sponsored partly by the retailers and/or manufacturers listed on this web page.
