The vacation season is upon us – a time of celebration, household gatherings, and let’s be sincere, metabolic challenges. From Thanksgiving dinner to Christmas events to New 12 months’s festivities, we’re about to face a gauntlet of scrumptious however fat- and carbohydrate-heavy meals that may wreak havoc on our blood sugar ranges and power.
Are you and your prospects prepared for the vacation energy? If not, formulate one thing like our GlucoVantage Vacation GDA in Formulator’s Nook #14. Keep in mind, it is a hypothetical method — construct the stack your self, or take the concept and run with it!
Whereas we imagine the vacations ought to be loved, we additionally know lots of our readers need to preserve their metabolic well being throughout this festive season. Whether or not you’re following a strict weight-reduction plan protocol (with or with out drugs) or simply making an attempt to remain wholesome by means of the winter months, supporting glucose metabolism turns into particularly essential this time of yr.
On this 14th version of our Formulator’s Nook, we’re making a hypothetical glucose disposal agent particularly designed for the vacation season. We’ve partnered with NNB Diet to develop a method that mixes their cutting-edge components with different confirmed compounds to assist help wholesome glucose metabolism while you want it most.
The Formulation: Vacation Glucose and Urge for food Optimization
For two capsules (really useful 2x every day):
GlucoVantage® (Dihydroberberine) – 150mg
CaloriBurn GP® (Grains of Paradise Extract) – 40mg
enfinity® (Paraxanthine) – 150mg
Chromax® (Chromium Picolinate) – 300mcg
Cinnamon Extract – 150mg
It is a stack you’ll be able to assemble your self from varied single-ingredient dietary supplements, or one which manufacturers can undertake in time for 2025.
Let’s break down why we selected every ingredient and the way they work collectively, however first, join our NNB Diet information alerts so that you don’t miss any information from the industry-leading novel ingredient builders:
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GlucoVantage® Dihydroberberine (150mg): The Superior Type of Berberine
On the core of our method is GlucoVantage dihydroberberine from NNB Diet, a patented,[1] extra bioavailable type of berberine that’s been proven to be 5 instances simpler than commonplace berberine.[2] Current analysis has revealed some fascinating mechanisms behind this ingredient:
Enhanced GLP-1 Secretion
Is Berberine “Nature’s Ozempic”? We check out their mechanisms as GLP-1 agonists, and reply, “Sure, considerably.”
New analysis exhibits berberine can promote GLP-1 amide secretion,[3-8] supporting wholesome metabolic operate
Past glucose uptake (talked about beneath), this additionally helps clarify why berberine has been traditionally profitable for blood sugar help
Superior Absorption
Dihydroberberine bypasses the conversion bottleneck that makes common berberine arduous to soak up[2]
This permits for decrease doses whereas sustaining efficacy
Particularly essential for these with compromised intestine well being, who typically have the best want for metabolic help[9]
Improved Glucose Uptake
Helps wholesome glucose disposal into muscle tissue
Helps preserve insulin sensitivity[10]
Significantly helpful when consuming vacation carbohydrates
Why 150mg per serving?
A examine printed in early 2022 confirmed that NNB Diet’s GlucoVantage dihydroberberine outperformed larger doses of regular berberine in elevating plasma berberine and lowering blood sugar and insulin ranges!
The 150mg dose we’ve chosen permits for twice-daily dosing whereas staying inside research-backed parameters.
Due to GlucoVantage’s superior bioavailability, that is considerably lower than the 1500mg of atypical berberine that’s typically required to maneuver the needle, but at this dose, it supplies comparable efficacy.
The 1500mg berberine dose is essential to check to, as a result of it was seen to outperform metformin — and with fewer unwanted effects![11]
Nonetheless, this serving continues to be sturdy sufficient for once-daily dosing, however actually meets its full potential if used twice every day for a giant vacation run.
There’s much more coming to GlucoVantage
As NNB’s Chief Science Officer Shawn Wells lately mentioned on Episode #152 of the PricePlow Podcast, there’s extra information coming for GlucoVantage as effectively.
We’ve written quite a few articles on dihydroberberine — for additional studying, learn the next:
CaloriBurn GP® (40mg): Activate Brown Adipose Tissue
CaloriBurn GP (standardized grains of paradise seed extract for 12.5% 6-paradol) enhances our method by supporting wholesome power expenditure by means of a captivating mechanism – the activation of brown adipose tissue (BAT).[12-14]
Shawn Wells and Dustin Elliott of NNB Diet be part of the PricePlow Podcast for Episode #152 to debate revolutionary components that seize ongoing traits like GLP-1 and MPS. We additionally get into Dustin’s journey to China, NNB’s participation in XPO NRG with MitoPrime, and Shawn’s psychedelic experiences and his post-trip complement stack.
Current pilot examine information from NNB Diet confirmed spectacular outcomes with their 160mg dose,[15] however we’ve opted for the clinically-validated 40mg dose since we’re recommending twice-daily use, and 40mg continues to be clinically-backed in people.[14,16]
Key advantages in our method:
Helps metabolic fee by means of BAT activation
Helps preserve wholesome power expenditure
Works synergistically with enfinity paraxanthine
We’ve coated CaloriBurn quite a few instances on the PricePlow Weblog, some nice articles to get extra info are beneath:
enfinity® Paraxanthine (150mg): Clear, Focused Power
As an alternative of utilizing commonplace caffeine, we’ve included enfinity paraxanthine – manufactured by NNB Diet and distributed by TSI Group. We used it for our XPO NRG challenge with huge success, and imagine that paraxanthine represents the way forward for power supplementation:
New analysis information has been printed on enfinity (paraxanthine), displaying elevated power expenditure in comparison with placebo (100 energy in 3 hours) — but it decreased urge for food and coronary heart fee![17]
Supplies the advantages of caffeine with out the downsides, equivalent to supporting lipolysis[18]
Common half-life of three.1 hours (vs. caffeine’s 4.1)[19]
Helps metabolic fee: new analysis exhibits elevated power expenditure whereas lowering starvation[17]
Helps cut back cognitive decline after exhaustive train[20]
The 150mg dose supplies noticeable power with out being overwhelming, permitting for 2 servings every day if wanted whereas avoiding late-day stimulant points.
For additional studying, see our article titled Paraxanthine: Caffeine’s Main Metabolite for Laser-Focused Power.
Chromax® Chromium Picolinate (300mcg): Supporting Wholesome Urge for food and Physique Composition
We’ve included a stable 300mcg dose of Chromax chromium picolinate per serving (600mcg every day), which analysis exhibits will help:
Help weight reduction[21] and wholesome physique composition[22,23]
Assist in urge for food administration[24]
Keep lean mass whereas weight-reduction plan[23]
The 600mg dose in two servings turns into particularly essential through the holidays when each urge for food administration and muscle preservation are key issues. If formulators actually need to go all-in, they will bump it to 1000mcg, which has one other examine displaying urge for food help.[25]
There’s way more info on the mechanism and research in our articles, “Chromium Picolinate: The Final Hint Mineral For Insulin Sensitivity“ and “Chromax Chromium Picolinate: 25+ Years of Insulin Sensitivity Enchancment“.
Cinnamon Extract (150mg): The Basic Insulin Mimicker
Rounding out our method is 150mg of cinnamon extract, a time-tested ingredient that:
Helps wholesome glucose metabolism[26-28]
Supplies antioxidant advantages
A key constituent in cinnamon is a polymer referred to as methylhydroxychalcone, which helps glucose clearance by mimicking insulin.[27,28]
We’ve seen bigger doses, however this enables us to suit every part into one capsule – any remaining room could be put in the direction of extra cinnamon as a “filler” when doable.
Synergistic Results
What makes this method particular is how the components work collectively:
Glucose Disposal Enhancement
We’ve lengthy stated that GlucoVantage dihydroberberine has 5x the bioavailability if conventional berberine. In our ‘5X’ article, we discover the very well-designed examine that demonstrated this.
GlucoVantage and Chromax work by means of totally different mechanisms to help wholesome insulin signaling
This twin method helps maximize nutrient partitioning round vacation meals
Metabolic Help
CaloriBurn GP prompts brown adipose tissue
enfinity paraxanthine helps power expenditure
Collectively they supply complementary metabolic help
Physique Composition Help
Chromax helps preserve lean mass
GlucoVantage helps nutrient partitioning
CaloriBurn GP prompts metabolically energetic tissue
Really helpful Use
For optimum outcomes:
Take 2 capsules 20-Half-hour earlier than your two largest meals of the day
Ultimate to be used earlier than vacation gatherings or giant meals
Because of the enfinity content material, keep away from taking your second serving after ~4PM
Can be utilized every day all through the vacation season
Good for Thanksgiving dinner, workplace events, and household gatherings
Who Is This For?
This method is designed for anybody eager to help wholesome glucose metabolism through the holidays and people seeking to preserve metabolic well being whereas having fun with seasonal festivities. It’s additionally nice for people searching for help with urge for food administration throughout a difficult season, in addition to anybody who desires to keep up their wholesome way of life by means of the winter months.
And if nothing else, the vacations are a superb time to show up the resistance coaching to additional help insulin sensitivity!
Conclusion: Supporting Vacation Well being
The vacation season doesn’t should imply fully abandoning our well being objectives. This method supplies complete help for:
Wholesome glucose metabolism
Power ranges
Metabolic operate
Physique composition
GlucoVantage from NNB Diet is a pure type of Dihydroberberine (DHB) and is named “The Tremendous Berberine”.
By combining cutting-edge components from NNB Diet with different research-supported compounds, we’ve ideated a method that might assist preserve metabolic well being throughout probably the most difficult time of the yr.
Keep in mind, dietary supplements like this work greatest alongside a nutritious diet and train program. Even through the holidays, sustaining sufficient protein consumption and a few type of common exercise will maximize the advantages of those components.
Join our NNB Diet information alerts to remain knowledgeable about these revolutionary components:
